Selected References
Mediouni, S., Jablonski, J. A., Tsuda, S., Barsamian, A., Kessing, C., Richard, A., Biswas, A., Toledo, F., Andrade, V. M., Even, Y., Stevenson, M., Tellinghuisen, T., et al. Oregano Oil and Its Principal Component, Carvacrol, Inhibit HIV-1 Fusion into Target Cells Journal of Virology 2020 94 DOI:10.1128/jvi.00147-20 PMID:32461309 PMCID:PMC7375364
Bird, G. H., Fu, A., Escudero, S., Godes, M., Opoku-Nsiah, K., Wales, T. E., Cameron, M. D., Engen, J. R., Danial, N. N., Walensky, L. D. Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor ACS Chemical Biology 2020 15:1340-1348 DOI:10.1021/acschembio.0c00308 PMID:32579931 PMCID:PMC7396151
Fassl, A., Brain, C., Abu-Remaileh, M., Stukan, I., Butter, D., Stepien, P., Feit, A. S., Bergholz, J., Michowski, W., Otto, T., Sheng, Q., Loo, A., et al. Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition Science Advances 2020 6 DOI:10.1126/sciadv.abb2210
Grim, T. W., Schmid, C. L., Stahl, E. L., Pantouli, F., Ho, J. H., Acevedo-Canabal, A., Kennedy, N. M., Cameron, M. D., Bannister, T. D., Bohn, L. M. A G protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal Neuropsychopharmacology 2020 45:416-425 DOI:10.1038/s41386-019-0491-8 PMID:31443104
Wang, J., Blasio, A., Chapman, H. L., Doebelin, C., Liaw, V., Kuryatov, A., Giovanetti, S. M., Lindstrom, J., Lin, L., Cameron, M. D., Kamenecka, T. M., Pomrenze, M. B., et al. Promoting activity of (α4)3(β2)2 nicotinic cholinergic receptors reduces ethanol consumption Neuropsychopharmacology 2020 45:301-308 DOI:10.1038/s41386-019-0475-8 PMID:31394567 PMCID:PMC6901472
Haniff, H. S., Knerr, L., Liu, X. H., Crynen, G., Bostrom, J., Abegg, D., Adibekian, A., Lekah, E., Wang, K. W., Cameron, M. D., Yildirim, I., Lemurell, M., et al. Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions Nature Chemistry 2020 12:952-961 DOI:10.1038/s41557-020-0514-4 PMID:32839603
Wu, Z. C., Cameron, M. D., Boger, D. L. Vancomycin C-Terminus Guanidine Modifications and Further Insights into an Added Mechanism of Action Imparted by a Peripheral Structural Modification ACS Infectious Diseases 2020 6:2169-2180 DOI:10.1021/acsinfecdis.0c00258 PMID:32598127 PMCID:PMC7429263
Hwang, D.*, Nilchan, N.*, Nanna, A. R., Li, X., Cameron, M. D., Roush, W. R., Park, H., Rader, C. Site-selective antibody functionalization via orthogonally reactive arginine and lysine residues Cell Chemical Biology 2019 26:1229-1239 DOI:10.1016/j.chembiol.2019.05.010 PMID:31231031 PMCID:PMC6754284 (* = equal contribution)
Su, M., Qiu, L., Deng, Y., Ruiz, C. H., Rudolf, J. D., Dong, L. B., Feng, X., Cameron, M. D., Shen, B., Duan, Y., Huang, Y. Evaluation of platensimycin and platensimycin-inspired thioether analogues against methicillin-resistant staphylococcus aureus in topical and systemic infection mouse models Molecular Pharmaceutics 2019 16:3065-3071 DOI:10.1021/acs.molpharmaceut.9b00293 PMID:31244223
To, C., Jang, J., Chen, T., Park, E., Mushajiang, M., De Clercq, D. J. H., Xu, M., Wang, S., Cameron, M. D., Heppner, D. E., Shin, B. H., Gero, T. W., et al. Single and dual targeting of mutant EGFR with an allosteric inhibitor Cancer Discovery 2019 9:926-943 DOI:10.1158/2159-8290.cd-18-0903 PMID:31092401
Angelbello, A. J., Rzuczek, S. G., McKee, K. K., Chen, J. L., Olafson, H., Cameron, M. D., Moss, W. N., Wang, E. T., Disney, M. D. Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model Proceedings of the National Academy of Sciences of the United States of America 2019 116:7799-7804 DOI:10.1073/pnas.1901484116 PMID:30926669 PMCID:PMC6475439
Guerrero, M., Urbano, M., Kim, E. K., Gamo, A. M., Riley, S., Abgaryan, L., Leaf, N., Van Orden, L. J., Brown, S. J., Xie, J. Y., Porreca, F., Cameron, M. D., et al. Design and synthesis of a novel and selective kappa opioid receptor (KOR) antagonist (BTRX-335140) Journal of Medicinal Chemistry 2019 62:1761-1780 DOI:10.1021/acs.jmedchem.8b01679 PMID:30707578 PMCID:PMC6395531
Doebelin, C., He, Y., Campbell, S., Nuhant, P., Kumar, N., Koenig, M., Garcia-Ordonez, R., Chang, M. R., Roush, W. R., Lin, L., Kahn, S., Cameron, M. D., et al. Discovery and optimization of a series of sulfonamide inverse agonists for the retinoic acid receptor-related orphan receptor-α Medicinal Chemistry 2019 15:676-684 DOI:10.2174/1573406415666190222124745 PMID:30799793
Amir, M., Chaudhari, S., Wang, R., Campbell, S., Mosure, S. A., Chopp, L. B., Lu, Q., Shang, J. S., Pelletier, O. B., He, Y., Doebelin, C., Cameron, M. D., et al. REV-ERBα regulates T(H)17 cell development and autoimmunity Cell Reports 2018 25:3733-3749 DOI:10.1016/j.celrep.2018.11.101 PMID:30590045
Kennedy, N. M., Schmid, C. L., Ross, N. C., Lovell, K. M., Yue, Z., Chen, Y. T., Cameron, M. D., Bohn, L. M., Bannister, T. D. Optimization of a series of mu opioid receptor (MOR) agonists with high G protein signaling bias Journal of Medicinal Chemistry 2018 61:8895-8907 DOI:10.1021/acs.jmedchem.8b01136 PMID:30199635
Fuerst, R., Yong Choi, J., Knapinska, A. M., Smith, L., Cameron, M. D., Ruiz, C., Fields, G. B., Roush, W. R. Development of matrix metalloproteinase-13 inhibitors – A structureactivity/structure-property relationship study Bioorganic & Medicinal Chemistry 2018 26:4984-4995 DOI:10.1016/j.bmc.2018.08.020 PMID:30249495
Grim, T. W., Park, S. J., Schmid, C. L., Laprairie, R. B., Cameron, M., Bohn, L. M. The effect of quinine in two bottle choice procedures in C57BL6 mice: Opioid preference, somatic withdrawal, and pharmacokinetic outcomes Drug and Alcohol Dependence 2018 191:195-202 DOI:10.1016/j.drugalcdep.2018.05.034 PMID:30138791191:195-202 DOI:10.1016/j.drugalcdep.2018.05.034 PMID:30138791
Mediouni, S., Jablonski, J. A., Tsuda, S., Richard, A., Kessing, C., Andrade, M. V., Biswas, A., Even, Y., Tellinghuisen, T., Choe, H., Cameron, M., Stevenson, M., et al. Potent suppression of HIV-1 cell attachment by Kudzu root extract Retrovirology 2018 15 DOI:10.1186/s12977-018-0446-x PMID:30236131 PMCID:PMC6149077